Asymmetric Synthesis of Dihydropyranones with Three Contiguous Stereocenters by an NHC?Catalyzed Kinetic Resolution

نویسندگان

چکیده

An oxidative NHC-catalyzed synthesis of tricyclic dihydropyranones with three contiguous stereocenters has been developed. Studies the mechanism suggest that rate-determining step is Breslow intermediate formation.

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ژورنال

عنوان ژورنال: European Journal of Organic Chemistry

سال: 2021

ISSN: ['1434-193X', '1099-0690']

DOI: https://doi.org/10.1002/ejoc.202100491