Asymmetric Synthesis of Dihydropyranones with Three Contiguous Stereocenters by an NHC?Catalyzed Kinetic Resolution
نویسندگان
چکیده
An oxidative NHC-catalyzed synthesis of tricyclic dihydropyranones with three contiguous stereocenters has been developed. Studies the mechanism suggest that rate-determining step is Breslow intermediate formation.
منابع مشابه
Asymmetric hydrogenation of α,α'-disubstituted cycloketones through dynamic kinetic resolution: an efficient construction of chiral diols with three contiguous stereocenters.
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2021
ISSN: ['1434-193X', '1099-0690']
DOI: https://doi.org/10.1002/ejoc.202100491